Pathogenic / Pathogenic mutations
Shared mutations
These mutations belong to the shared level-up pool. Values describe one copy before other run bonuses. Pathogen-specific Amoeba evolutions and Nanobot block mutations are outside this catalogue.
| Mutation | Effect per copy | DNA room |
|---|---|---|
| +0.75% damage for each point of thrust from flagella | Eligible for the three-copy offer | |
| +40% damage and +40% attack speed when at 2 or less HP | Eligible for the three-copy offer | |
| Gain 3 cores when getting hit | Eligible for the three-copy offer | |
| +100% damage Take double damage | Excluded from the three-copy offer | |
| +0.5% damage for each core (Currently +0.0%) | Eligible for the three-copy offer | |
| First attack after 3 seconds of no attacking deals +100% damage | Eligible for the three-copy offer | |
| Active Abilities activate automatically as soon as they are charged, and need 25% less overcharge time to charge | Excluded from the three-copy offer | |
| Combat Active Abilities slowly charge up on their own | Eligible for the three-copy offer | |
| 15% chance to spawn a heart after finishing a room | Eligible for the three-copy offer | |
| +15% damage for each pseudopod that was attached in the last 0.5s | Eligible for the three-copy offer | |
| +20% base speed | Eligible for the three-copy offer | |
| Turn a random internal slot into a +40% overcharge strength slot | Eligible for the three-copy offer | |
| +10% damage | Eligible for the three-copy offer | |
| Frozen enemies take +50% damage | Eligible for the three-copy offer | |
| Weapons on the right half of the body deal +100% damage Weapons on the left deal -50% damage | Eligible for the three-copy offer | |
| Attract DNA pickups from +400% farther | Eligible for the three-copy offer | |
| +1 stash slot to store organelles | Eligible for the three-copy offer | |
| Gain a random mitochondrion | Eligible for the three-copy offer | |
| -30% dodge cooldown | Excluded from the three-copy offer | |
| Makes a random external slot also accept internal organelles | Eligible for the three-copy offer | |
| +15% attack speed | Eligible for the three-copy offer | |
| +200% damage -50% damage for each weapon | Eligible for the three-copy offer | |
| +40% lightning split chance | Eligible for the three-copy offer | |
| Reroll ALL equipped organelles Gain a random weapon +25% damage | Eligible for the three-copy offer | |
| Weapons no longer consume stamina -0.3× damage | Excluded from the three-copy offer | |
| +1 stamina container | Eligible for the three-copy offer | |
| Dodging restores +1 stamina container | Eligible for the three-copy offer | |
| 40% chance to spawn 1 HP when getting hit by explosions and self-damage | Eligible for the three-copy offer | |
| +1 dodge charge | Eligible for the three-copy offer | |
| Makes a random internal slot also accept external organelles | Eligible for the three-copy offer | |
| +25% range of projectiles, melee attacks and areas of effect | Eligible for the three-copy offer | |
| Gain 5 to 20 cores | Eligible for the three-copy offer | |
| Fully restore HP | Excluded from the three-copy offer | |
| Active Abilities require 35% less overcharge time to activate | Eligible for the three-copy offer | |
| +15% overcharge strength from mitochondria mitochondria | Eligible for the three-copy offer | |
| +3 DNA and +3 cores for recycling organelles | Eligible for the three-copy offer | |
| +15% damage of melee attacks | Eligible for the three-copy offer | |
| Your minions release a 100 damage splash attack every time they're hit | Eligible for the three-copy offer | |
| Gain a random weapon | Eligible for the three-copy offer | |
| Shop prices are 25% cheaper | Eligible for the three-copy offer | |
| +3 armor | Eligible for the three-copy offer | |
| The next mutation you pick is applied twice | Eligible for the three-copy offer | |
| +20% damage for each empty internal slot internal organelle slot | Eligible for the three-copy offer | |
| When a burning enemy dies, the burn jumps to the closest enemy | Eligible for the three-copy offer | |
| Gain a random attack infuser | Eligible for the three-copy offer | |
| +1 max HP | Eligible for the three-copy offer | |
| +15% damage for each active mitochondria mitochondrion | Eligible for the three-copy offer | |
| Gain 5 to 15 DNA | Eligible for the three-copy offer | |
| +15% chance for organelle rewards to spawn at a higher rarity | Eligible for the three-copy offer | |
| Weapons on the left half of the body deal +100% damage Weapons on the right deal -50% damage | Eligible for the three-copy offer | |
| +3 mutation reroll(s) | Eligible for the three-copy offer | |
| Up to +15% damage for each empty stamina container | Eligible for the three-copy offer | |
| -50% projectile spread | Eligible for the three-copy offer | |
| +0.2s dodge invulnerability | Excluded from the three-copy offer | |
| Enemy projectiles move 25% slower | Eligible for the three-copy offer | |
| Turn a random external slot into a +40% damage slot | Eligible for the three-copy offer |
Checked October 3, 2026. Sources & coverage. Unofficial.